SCHEMBL2197495

SCHEMBL2197495

CCCCN(CCCC)C(=O)NCCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA9 Q16790 2/20 0.45
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP3 P08254 1/20 0.42
MMP8 P22894 1/20 0.42
ALDH1A1 P00352 4/20 0.41
ALDH2 P05091 1/20 0.41
NTRK2 Q16620 1/20 0.40
NAAA Q02083 1/20 0.40
DNM1 Q05193 1/20 0.40
CNR1 P21554 3/20 0.39
MEN1 O00255 2/20 0.39
BLM P54132 2/20 0.39
KMT2A Q03164 2/20 0.39
TRPV1 Q8NER1 2/20 0.39
SELP P16109 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
FAAH O00519 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763583 0.96 CA12 (0.42) CA12CA1CA9MMP1MMP2
SCHEMBL2194869 0.90 CA12 (0.44) CA12CA1CA9MMP1MMP2
SCHEMBL8394144 0.89 NAAA (0.43) ALDH1A1NAAADNM1CNR1MEN1
SCHEMBL27685014 0.89 ACHE (0.45) CA12CA1CA9MMP1MMP2
SCHEMBL27684966 0.89 ACHE (0.44) CA12CA1CA9MMP1MMP2
SCHEMBL18531295 0.88 CA12 (0.48) CA12CA1CA9MMP1MMP2
SCHEMBL6835933 0.88 EPHX1 (0.48) CA12CA1CA9MMP1MMP2
SCHEMBL25227149 0.86 EPHX1 (0.54) CA12CA1CA9MMP1MMP2
SCHEMBL424525 0.86 EPHX1 (0.54) CA12CA1CA9MMP1MMP2
SCHEMBL6276546 0.85 NTRK2 (0.51) ALDH1A1NTRK2MEN1BLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150673-B2 Process for preparing (meth)acrylic esters BASF SE (DE) 2015-10-06 US disclosed
US-20130178592-A1 PROCESS FOR PREPARING (METH)ACRYLIC ESTERS BASF SE (DE) 2013-07-11 US disclosed
US-8263371-B2 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides BASF AKTIENGESELLSCHAFT (DE) 2012-09-11 US disclosed
US-7993886-B2 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides BASF AKTIENGESELLSHAFT (DE) 2011-08-09 US disclosed
US-20110171697-A1 CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES BASF AKTIENGESELLSHAFT (DE) 2011-07-14 US disclosed
US-20100285542-A1 CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES BASF AKTIENGESELLSHAFT (DE) 2010-11-11 US disclosed
US-7816485-B2 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides BASF AKTIENGESELLSCHAFT (DE) 2010-10-19 US disclosed
US-20060036063-A1 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides BASF AKTIENGESELLSCHAFT (DE) 2006-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100285542-A1 CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES NAAA, APEH, NAA15 CA12 1699/4885CA1 1754/4885CA9 808/4885
US-20110171697-A1 CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES NAAA, APEH, NAA15 CA12 1699/4885CA1 1754/4885CA9 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.