SCHEMBL2197501

SCHEMBL2197501

Brc1cccc(CI)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29756502 0.81 TAAR1 (0.63)
SCHEMBL6500358 0.81 TAAR1 (0.63)
SCHEMBL646951 0.81 ALDH1A1 (0.43)
SCHEMBL1607086 0.80
SCHEMBL4399626 0.79 TAAR1 (0.74)
SCHEMBL9200966 0.79 TAAR1 (0.60)
SCHEMBL7596449 0.78 TAAR1 (0.59)
SCHEMBL29353789 0.77
SCHEMBL6882 0.77
SCHEMBL1044821 0.76 TAAR1 (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017117687-A1 18/19F-LABELLED COMPOUNDS WHICH TARGET THE PROSTATE SPECIFIC MEMBRANE ANTIGEN BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) 2017-07-13 WO disclosed
WO-2013138413-A1 BIS-QUARTERNARY CINCHONA ALKALOID SALTS AS ASYMMETRIC PHASE TRANSFER CATALYSTS MERCK SHARP & DOHME CORP. (US) 2013-09-19 WO disclosed
US-7977387-B2 Aminobenzophenone compounds LEO PHARMA A/S (DK) 2011-07-12 US disclosed
CN-1826310-B Novel aminobenzophenone compounds LEO PHARMA AS 2010-07-21 CN disclosed
US-20100137388-A1 Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof DENOVAMED INC. (CA) 2010-06-03 US disclosed
US-20100137388-A1 Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof DENOVAMED INC. (CA) 2010-06-03 US disclosed
US-20100137388-A1 Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof DENOVAMED INC. (CA) 2010-06-03 US disclosed
WO-2008128321-A1 THERAPEUTIC PRO-ANTIBIOTIC AGENTS AND METHODS OF USE THEREOF DENOVAMED INC. (CA) 2008-10-30 WO disclosed
WO-2008128321-A1 THERAPEUTIC PRO-ANTIBIOTIC AGENTS AND METHODS OF USE THEREOF DENOVAMED INC. (CA) 2008-10-30 WO disclosed
CN-1826310-A Novel aminobenzophenone compounds LEO PHARMA AS (DK) 2006-08-30 CN disclosed
US-20060166990-A1 Novel aminobenzophenone compounds LEO PHARMA A/S (DK) 2006-07-27 US disclosed
EP-1159314-B1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEM CO (US) 2004-08-04 EP disclosed
CN-1138793-C Process for producing polyethylene �Ϻ���ͨ��ѧ 2004-02-18 CN disclosed
US-6534613-B2 Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst EASTMAN CHEMICAL COMPANY 2003-03-18 US disclosed
CN-1332753-A Process for producing polyethylene EASTMAN CHEM CO (US) 2002-01-23 CN disclosed
US-20020007024-A1 Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst WESTLAKE LONGVIEW CORPORATION 2002-01-17 US disclosed
EP-1159314-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2001-12-05 EP disclosed
WO-2000052067-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed