SCHEMBL646951

SCHEMBL646951

ICc1cccc(CI)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
ALOX12 P18054 2/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
CASP1 P29466 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
IDO1 P14902 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9313214 0.91 MEN1 (0.46) ALDH1A1ALOX12HPGDALOX15CASP1
SCHEMBL8645715 0.87 ALDH1A1 (0.40) ALDH1A1ALOX12HPGDALOX15CASP1
SCHEMBL2666166 0.87 TP53 (0.48) ALDH1A1CYP1A2GRIN2DGRIN3BGRIN1
SCHEMBL5981892 0.87 ENPP2 (0.50) ENPP2NOS3NOS1NOS2
SCHEMBL16624583 0.87 LOXL2 (0.55) ALDH1A1LOXL2PNMTENPP2NOS3
SCHEMBL283667 0.83
SCHEMBL10167472 0.83 TAAR1 (0.57) ALDH1A1ALOX15HSD17B10LOXL2PNMT
SCHEMBL13313981 0.83 CNR1 (0.42) ALDH1A1ALOX12HPGDALOX15CASP1
SCHEMBL5675646 0.81
SCHEMBL2197501 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119368027-A Composite nanofiltration membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-01-28 CN claimed
US-4016194-A CATALYTIC CARBONYLATION TEXACO INC. (US) 1977-04-05 US claimed
US-20260109853-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-23 US disclosed
US-20260109854-A1 CURABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-23 US disclosed
US-12595334-B2 Compound, mixture, curable resin composition and cured product thereof, and method for producing compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-07 US disclosed
WO-2024253039-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT THEREOF 日本化薬株式会社 2024-12-12 WO disclosed
WO-2024225185-A1 ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION FOR CROSSLINKING, AND CROSSLINKED OBJECT OBTAINED THEREFROM 株式会社大阪ソーダ 2024-10-31 WO disclosed
WO-2024219273-A1 CURABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF 日本化薬株式会社 2024-10-24 WO disclosed
WO-2024219272-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME 日本化薬株式会社 2024-10-24 WO disclosed
WO-2024203532-A1 CURABLE RESIN COMPOSITION, PREPREG, AND CURED PRODUCTS THEREOF 日本化薬株式会社 2024-10-03 WO disclosed
WO-2024195765-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT THEREOF 日本化薬株式会社 2024-09-26 WO disclosed
US-5106953-A Reacting aromatic amines with bishalogenomethyl derivatives; curing agents or raw materials for polyamides MITSUI TOATSU CHEMICALS, INC. (JP) 1992-04-21 US disclosed
US-5051494-A A bismaleimide and an amino resin MITSUI TOATSU CHEMICALS, INC. (JP) 1991-09-24 US disclosed
US-4981768-A Photosensitive recording material having an N-aryl carbazole p-type charge transport compound AGFA-GEVAERT, N.V. (BE) 1991-01-01 US disclosed
US-4943502-A TWO LAYER SYSTEM OF CHARGE GENERATING AND CHARGE TRANSPORTING COMPOUNDS AGFA-GEVAERT, N.V. (BE) 1990-07-24 US disclosed
US-4937318-A Aromatic amine resins MITSUI TOATSU CHEMICALS, INC. (JP) 1990-06-26 US disclosed
EP-0347960-A1 Photosensitive recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1989-12-27 EP disclosed
EP-0347967-A1 Photosensitive recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1989-12-27 EP disclosed
CN-1032806-A Aromatic amine resin, its preparation method and application in thermosetting resin composition MITSUI TOATSU CHEMICALS (JP) 1989-05-10 CN disclosed
EP-0311387-A2 Aromatic amine resins, their production process and thermosetting resin compositions making use of the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109854-A1 CURABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF MLLT1, CRBN, POT1 ALDH1A1 2301/4885ALOX12 866/4885HPGD 3074/4885
US-20260109853-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME PSMA1, PSMB10, RAD51 ALDH1A1 438/4885ALOX12 345/4885HPGD 1608/4885
US-12595334-B2 Compound, mixture, curable resin composition and cured product thereof, and method for producing compound RER1, RXRA, TERB1 ALDH1A1 1225/4885ALOX12 313/4885HPGD 2606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.