Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL567278 | 1.00 | S1PR4 (0.30) | S1PR4S1PR1 | |
| Trifluoroacetic Acid SCHEMBL2202675 | 1.00 | S1PR4 (0.30) | S1PR4S1PR1 | |
| Trifluoroacetic Acid SCHEMBL20548257 | 0.94 | S1PR4 (0.33) | S1PR4S1PR1 | |
| Trifluoroacetic Acid SCHEMBL567106 | 0.94 | S1PR4 (0.33) | S1PR4S1PR1 | |
| Trifluoroacetic Acid SCHEMBL20261710 | 0.92 | — | — | |
| Trifluoroacetic Acid SCHEMBL566660 | 0.92 | — | — | |
| SCHEMBL1919728 | 0.89 | MCHR1 (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL566855 | 0.87 | — | — | |
| Trifluoroacetic Acid SCHEMBL16872584 | 0.84 | S1PR4 (0.32) | S1PR4S1PR1 | |
| Trifluoroacetic Acid SCHEMBL565836 | 0.81 | S1PR4 (0.33) | S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283438-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-11-08 | — | — | US | disclosed |
| US-20110269781-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-7977344-B2 | Compounds | GLAXOSMITHKLINE LLC (US) | 2011-07-12 | — | — | US | disclosed |
| EP-2125792-B1 | PURINE DERIVATIVES AS IMMUNOMODULATORS | GLAXOSMITHKLINE LLC (US) | 2010-12-01 | — | — | EP | disclosed |
| US-20100120799-A1 | PURINE DERIVATIVES AS IMMUNOMODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| US-20090131458-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283438-A1 | COMPOUNDS | LTC4S, LTB4R2, LTB4R | S1PR4 603/4885S1PR1 480/4885 |
| US-20090131458-A1 | Compounds | LTC4S, LTB4R2, LTB4R | S1PR4 603/4885S1PR1 480/4885 |
| US-20100120799-A1 | PURINE DERIVATIVES AS IMMUNOMODULATORS | LTC4S, STING1, LTB4R2 | S1PR4 847/4885S1PR1 418/4885 |
| US-20110269781-A1 | COMPOUNDS | LTC4S, LTB4R2, LTB4R | S1PR4 603/4885S1PR1 480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.