⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13388151 | 0.81 | MAOB (0.67) | — | |
| SCHEMBL3322552 | 0.78 | MAOB (0.70) | — | |
| SCHEMBL7737312 | 0.78 | MAOB (0.70) | — | |
| SCHEMBL155054 | 0.75 | MAOB (1.00) | — | |
| SCHEMBL74275 | 0.75 | MAOB (0.67) | — | |
| SCHEMBL155055 | 0.75 | MAOB (1.00) | — | |
| SCHEMBL1524697 | 0.75 | MAOB (1.00) | — | |
| SCHEMBL6017301 | 0.74 | CYP2A6 (0.44) | — | |
| SCHEMBL10784522 | 0.73 | — | — | |
| Phenylacetaldehyde SCHEMBL18972 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278797-B | Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium | 株式会社力森诺科 | 2023-06-16 | — | — | CN | claimed |
| CN-110997625-B | Fluorinated ether compound, lubricant for magnetic recording medium, and magnetic recording medium | 昭和电工株式会社 | 2023-03-31 | — | — | CN | claimed |
| CN-110225895-B | Base protective film, adhesion preventing member, and method for forming adhesion preventing member | 星和电机株式会社 | 2021-11-02 | — | — | CN | claimed |
| CN-108264515-B | Benzo [ def ] carbazole compounds and preparation method and application thereof | 中国科学院上海药物研究所 | 2021-01-12 | — | — | CN | claimed |
| EP-2951179-B1 | SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS | MERCK PATENT GMBH (DE) | 2020-03-11 | — | — | EP | claimed |
| CN-107445935-B | Hesperetin analog derivative and its preparation that a kind of amide groups replaces and as the application in anti-inflammatory drug | 安徽医科大学 | 2019-09-27 | — | — | CN | claimed |
| CN-108822160-B | The application of mixed matching nickel (II) complex based on phosphite ester and unsaturated nitrogen heterocycle carbine | 苏州大学 | 2019-09-17 | — | — | CN | claimed |
| CN-110225895-A | Matrix protective film, attachment prevent component and attachment from preventing the forming method of component | 星和电机株式会社 | 2019-09-10 | — | — | CN | claimed |
| CN-106986840-B | A kind of synthetic method of polysubstituted 2,3- dihydro-isoxazole class compound | 湖北科技学院 | 2019-08-20 | — | — | CN | claimed |
| CN-106905280-B | Hesperetin analog derivative that a kind of amide groups replaces and preparation method thereof and as the application in the drug of anti-alzheimer's disease | 安徽医科大学 | 2019-04-09 | — | — | CN | claimed |
| US-5461074-A | Dipropargyl containing aryl/alkyl sulfur/or sulfonyl/or sulfoxide terminated aminodiol compounds are used as renin inhibitor; therpeutical | G.D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | claimed |
| US-5432201-A | Alkylaminoalkyl-sulfonyl-terminated β-alanineamide amino-diol compounds for treatment of hypertension | G. D. SEARLE & CO. (US) | 1995-07-11 | — | — | US | claimed |
| US-5416119-A | Alkylaminoalkyl-terminated sulfide/sulfonyl-containing cycloalkyl-alanine amino-diol compounds for treatment of hypertension | G. D. SEARLE & CO. (US) | 1995-05-16 | — | — | US | claimed |
| US-5414018-A | Alkylaminoalkyl-terminated sulfide/sulfonyl-containing propargyl amino-diol compounds for treatment of hypertension | G. D. SEARLE & CO. (US) | 1995-05-09 | — | — | US | claimed |
| WO-1995008531-A1 | ALKYLAMINOALKYL-TERMINATED SULFIDE/SULFONYL-CONTAINING PROPARGYL AMINO-DIOL COMPOUNDS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1995-03-30 | — | — | WO | claimed |
| US-5317039-A | Renin inhibitors with peptides | G. D. SEARLE & CO. (US) | 1994-05-31 | — | — | US | claimed |
| US-5314920-A | Renin inhibitors | G. D. SEARLE & CO. (US) | 1994-05-24 | — | — | US | claimed |
| US-5312838-A | β-alanineamide aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension | G. D. SEARLE & CO. (US) | 1994-05-17 | — | — | US | claimed |
| US-5268391-A | Cardiovascular disorders | C. D. SEARLE & CO. (US) | 1993-12-07 | — | — | US | claimed |
| US-5246969-A | Oligopeptides as renin inhibitors | G. D. SEARLE & CO. (US) | 1993-09-21 | — | — | US | claimed |