Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18193947 | 0.94 | APP (0.55) | APPHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL18382266 | 0.94 | APP (0.51) | APPHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL18382281 | 0.94 | APP (0.51) | APPHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL18382282 | 0.92 | APP (0.49) | APPHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL18382287 | 0.90 | APP (0.55) | APPHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL16596776 | 0.89 | APP (0.44) | APPHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL8994693 | 0.89 | APP (0.43) | APPCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL15591234 | 0.88 | APP (0.49) | APPHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL8994780 | 0.88 | APP (0.49) | APPHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL18382283 | 0.88 | APP (0.47) | APPHSD17B1HSD17B2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110518451-B | Temperature-controlled aggregation laser, preparation method and optical switch application | 华南理工大学 | 2020-06-02 | — | — | CN | claimed |
| US-20210387994-A1 | SOLVENT-FREE CROSS-COUPLING REACTION, AND PRODUCTION METHOD USING SAID REACTION | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2021-12-16 | — | — | US | disclosed |
| CN-110518451-B | Temperature-controlled aggregation laser, preparation method and optical switch application | 华南理工大学 | 2020-06-02 | — | — | CN | disclosed |
| WO-2020085396-A1 | SOLVENT-FREE CROSS-COUPLING REACTION, AND PRODUCTION METHOD USING SAID REACTION | 国立大学法人北海道大学 | 2020-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387994-A1 | SOLVENT-FREE CROSS-COUPLING REACTION, AND PRODUCTION METHOD USING SAID REACTION | MCCC2, CTRC, DDC | APP 3167/4885HSD17B1 597/4885HSD17B2 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.