Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199594 | 0.96 | KCNA5 (0.41) | KCNA5KCND3CYP19A1ATMKMT2A | |
| SCHEMBL2198631 | 0.91 | ATM (0.45) | KCNA5KCND3CYP19A1ATMKMT2A | |
| SCHEMBL2197035 | 0.91 | ATM (0.45) | KCNA5KCND3CYP19A1ATMKMT2A | |
| SCHEMBL2199854 | 0.90 | CYP19A1 (0.44) | KCNA5KCND3CYP19A1ATMKMT2A | |
| SCHEMBL2200038 | 0.88 | CYP19A1 (0.40) | KCNA5KCND3CYP19A1ATMKMT2A | |
| SCHEMBL2197190 | 0.87 | SMN1; SMN2 (0.47) | KCNA5KCND3CYP19A1ATMKMT2A | |
| SCHEMBL2197845 | 0.86 | KCNA5 (0.47) | KCNA5KCND3CYP19A1CYP17A1SMN1; SMN2 | |
| SCHEMBL2194575 | 0.86 | ATM (0.38) | KCNA5KCND3CYP19A1ATMKMT2A | |
| SCHEMBL2196056 | 0.85 | ATM (0.49) | ATMKMT2ACYP17A1SMN1; SMN2LMNA | |
| SCHEMBL12424176 | 0.85 | BRD4 (0.43) | KCNA5KCND3ATMKMT2ACYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | claimed |
| US-20100179059-A1 | Fungicidal Mixtures | BASF SE (DE) | 2010-07-15 | — | — | US | claimed |
| EP-2170071-A2 | FUNGICIDAL MIXTURES | BASF SE (DE) | 2010-04-07 | — | — | EP | claimed |
| WO-2008148859-A2 | FUNGICIDAL MIXTURES | BASF SE (DE) | 2008-12-11 | — | — | WO | claimed |
| US-20080167350-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2008-07-10 | — | — | US | claimed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | claimed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | claimed |
| EP-1794167-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | Syngenta Limited (GB) | 2007-06-13 | — | — | EP | claimed |
| US-20060073971-A1 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2006-04-06 | — | — | US | claimed |
| WO-2006031631-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2006-03-23 | — | — | WO | claimed |
| WO-2013011010-A1 | FUNGIZIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013011010-A1 | FUNGIZIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013007550-A1 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-17 | — | — | WO | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| US-20060073971-A1 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167350-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | CYP4X1, CYP51A1, CYP3A7 | KCNA5 850/4885KCND3 1175/4885CYP19A1 19/4885 |
| US-20100179059-A1 | Fungicidal Mixtures | ARSA, AADAC, TYR | KCNA5 127/4885KCND3 871/4885CYP19A1 1523/4885 |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | CYP4X1, CYP51A1, CYP3A7 | KCNA5 760/4885KCND3 1227/4885CYP19A1 21/4885 |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | CYP4Z1, CYP4X1, AGXT | KCNA5 1858/4885KCND3 2559/4885CYP19A1 598/4885 |
| US-20060073971-A1 | Substituted isoxazoles as fungicides | CYP4X1, CYP51A1, CYP3A7 | KCNA5 750/4885KCND3 1046/4885CYP19A1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.