Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172709 | 0.91 | MEN1 (0.44) | MEN1CYP2C19RECQLKMT2ARNPEP | |
| SCHEMBL6785594 | 0.84 | MEN1 (0.48) | MEN1CYP2C19RECQLKMT2ACTSK | |
| SCHEMBL23810002 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2ARNPEPCTSKMAPT | |
| SCHEMBL30680094 | 0.83 | CTSK (0.41) | MEN1CYP2C19RECQLKMT2ACTSK | |
| SCHEMBL5391791 | 0.83 | MGAM (0.43) | RNPEPCTSKMAPTMAPK1CYP19A1 | |
| SCHEMBL606963 | 0.82 | RNPEP (0.39) | RNPEPCTSKCYP19A1CACNA2D1CACNB3 | |
| SCHEMBL12662795 | 0.82 | ALDH1A1 (0.43) | MEN1CYP2C19RECQLKMT2ALMNA | |
| SCHEMBL12136572 | 0.82 | CACNA2D1 (0.46) | MEN1CYP2C19RECQLKMT2AMAPT | |
| SCHEMBL10923718 | 0.80 | MEN1 (0.43) | MEN1CYP2C19RECQLKMT2AMAPT | |
| SCHEMBL14088060 | 0.80 | TSHR (0.44) | MEN1KMT2ARNPEPCTSKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3506754-B1 | PICOLINAMIDE N-OXIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |