SCHEMBL2197767

SCHEMBL2197767

O=S(=O)([O-])OCO.O=S(=O)([O-])OCO.[Cu+2]

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
RECQL P46063 2/20 0.36
TSHR P16473 2/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
EPHX2 P34913 1/20 0.36
BLM P54132 1/20 0.36
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1876612 1.00 TP53 (0.36) TP53RECQLTSHRGLAHPGD
SCHEMBL1876123 1.00 TP53 (0.36) TP53RECQLTSHRGLAHPGD
SCHEMBL1919202 0.94
SCHEMBL11056131 0.94 TP53 (0.36) TP53RECQLTSHRGLAHPGD
Zinc Ion SCHEMBL3757128 0.94 TP53 (0.36) TP53RECQLTSHRGLAHPGD
SCHEMBL4523290 0.71 RECQL (0.43) TP53RECQLTSHRGLAHPGD
SCHEMBL2313305 0.71
Potassium Ion SCHEMBL340574 0.71
Lithium Ion SCHEMBL16146112 0.71
SCHEMBL7603680 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133512-B2 System for determining amino acid sequence of polypeptide CHUNG YUAN CHRISTIAN UNIVERSITY (TW) 2015-09-15 US claimed
US-20140170759-A1 SYSTEM AND METHOD FOR DETERMINING AMINO ACID SEQUENCE OF POLYPEPTIDE CHUNG YUAN CHRISTIAN UNIVERSITY (TW) 2014-06-19 US claimed
US-10221435-B2 DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same MITSUI CHEMICALS, INC. (JP) 2019-03-05 US disclosed
US-20170327853-A1 DNA ENCODING NOVEL ENZYME HAVING D-SERINE SYNTHASE ACTIVITY, METHOD OF PRODUCING THE ENZYME AND METHOD OF PRODUCING D-SERINE BY USING THE SAME MITSUI CHEMICALS, INC. (JP) 2017-11-16 US disclosed
US-7977073-B2 Polynucleotide encoding a thermostable amide hydrolase and methods for producing an L-α-amino acid MITSUBISHI RAYON CO., LTD. (JP) 2011-07-12 US disclosed
US-20090215132-A1 Novel amide hydrolase gene MITSUBISHI RAYON CO., LTD. (JP) 2009-08-27 US disclosed
EP-2050738-A1 NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID Kaneka Corporation (JP) 2009-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215132-A1 Novel amide hydrolase gene ASPH, NAAA, APEH TP53 3009/4885RECQL 3393/4885TSHR 1892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.