SCHEMBL21980088

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28905919	0.81	CYP1A2 (0.53)	BACE1CYP2A6ALDH1A1CYP1A2KDM4E
	SCHEMBL727654	0.80	BACE1 (0.53)	BACE1L3MBTL1CYP2A6TLR2KDM4E
	SCHEMBL12144961	0.76	BACE1 (0.42)	BACE1THRBL3MBTL1TLR2ALDH1A1
	SCHEMBL4278377	0.74	CYP1A2 (0.47)	BACE1ALDH1A1CYP1A2KDM4EMEN1
	SCHEMBL31754005	0.73	BACE1 (0.46)	BACE1THRBL3MBTL1CYP2A6TLR2
	SCHEMBL13196951	0.73	BACE1 (0.40)	BACE1THRBL3MBTL1TLR2MEN1
	SCHEMBL1161750	0.73	KCNH2 (0.40)	BACE1MAPT
	SCHEMBL1161752	0.73	KCNH2 (0.40)	BACE1MAPT
	SCHEMBL27259576	0.73	F2 (0.41)	BACE1THRBL3MBTL1CYP2A6ALDH1A1
	SCHEMBL10220222	0.73	BACE1 (0.53)	BACE1CYP2A6TLR2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.