Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893000 | 0.83 | — | — | |
| SCHEMBL8648156 | 0.82 | — | — | |
| SCHEMBL10566631 | 0.78 | TSHR (0.38) | LMNATSHR | |
| SCHEMBL789558 | 0.76 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL23015167 | 0.74 | LMNA (0.36) | SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL1535208 | 0.74 | LMNA (0.36) | SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL23014944 | 0.74 | LMNA (0.36) | SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL23015187 | 0.74 | LMNA (0.36) | SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL14881122 | 0.74 | — | — | |
| SCHEMBL8800313 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149479-A1 | SYNTHESIS OF MODIFIED NUCLEOSIDE TRIPHOSPHATES | ROCHE DIAGNOSTICS GMBH (DE) | 2025-07-17 | — | — | WO | disclosed |
| US-20230135188-A1 | FE/CU-MEDIATED KETONE SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-05-04 | — | — | US | disclosed |
| US-11498892-B2 | Fe/Cu-mediated ketone synthesis | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-11-15 | — | — | US | disclosed |
| US-20210179522-A9 | FE/CU-MEDIATED KETONE SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-17 | — | — | US | disclosed |
| US-20200165183-A1 | FE/CU-MEDIATED KETONE SYNTHESIS | President and Fellows of Flarvard College (US) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179522-A9 | FE/CU-MEDIATED KETONE SYNTHESIS | TKT, COASY, FECH | SMN1; SMN2 4362/4885ALDH1A1 812/4885LMNA 3467/4885 |
| US-20200165183-A1 | FE/CU-MEDIATED KETONE SYNTHESIS | TKT, COASY, FECH | SMN1; SMN2 4362/4885ALDH1A1 812/4885LMNA 3467/4885 |
| US-11498892-B2 | Fe/Cu-mediated ketone synthesis | TKT, COASY, FECH | SMN1; SMN2 4362/4885ALDH1A1 812/4885LMNA 3467/4885 |
| US-20230135188-A1 | FE/CU-MEDIATED KETONE SYNTHESIS | TKT, COASY, FECH | SMN1; SMN2 4362/4885ALDH1A1 812/4885LMNA 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.