SCHEMBL2198185

SCHEMBL2198185

CS(=O)(=O)CCCS(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.50
LMNA P02545 2/20 0.41
PTGS1 P23219 1/20 0.41
PDE4A P27815 1/20 0.41
SLC6A6 P31641 1/20 0.41
CYP2C19 P33261 1/20 0.41
BLM P54132 1/20 0.41
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
NLRP3 Q96P20 1/20 0.36
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476377 0.94 APP (0.50) APPLMNAPTGS1PDE4ASLC6A6
SCHEMBL27026941 0.92 APP (0.48) APPLMNAPTGS1PDE4ASLC6A6
Eprodisate SCHEMBL34216 0.84 APP (0.65) APPLMNAPTGS1PDE4ASLC6A6
SCHEMBL3913999 0.84 ALDH1A1 (0.46) LMNACYP2C19ALDH1A1TP53NLRP3
SCHEMBL13321333 0.83 APP (0.41) APPLMNAPTGS1PDE4ASLC6A6
SCHEMBL26323059 0.82 APP (0.50) APPLMNAPTGS1PDE4ASLC6A6
SCHEMBL11695951 0.81 LMNA (0.45) APPLMNAPTGS1PDE4ASLC6A6
Eprodisate SCHEMBL23795563 0.81 APP (0.61) APPLMNAPTGS1PDE4ASLC6A6
Eprodisate SCHEMBL2288862 0.81 APP (0.61) APPLMNAPTGS1PDE4ASLC6A6
Eprodisate SCHEMBL2522163 0.81 APP (0.61) APPLMNAPTGS1PDE4ASLC6A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2630129-B1 QUINOXALINE DERIVATES MERCK PATENT GMBH (DE) 2016-10-26 EP claimed
US-8895559-B2 Quinoxalines derivatives and pharmaceutical compositions and kits MERCK PATENT GMBH (DE) 2014-11-25 US claimed
US-20130217670-A1 QUINOXALINE DERIVATIVES MERCK PATENT GMBH (DE) 2013-08-22 US claimed
US-11912882-B2 Ink set SEIKO EPSON CORPORATION (JP) 2024-02-27 US disclosed
US-20240018376-A1 AQUEOUS ADDITIVE SOLUTION FOR INK COMPOSITION, AQUEOUS COLORANT SOLUTION FOR INK COMPOSITION, INK COMPOSITION, INK COMPOSITION FOR INK JET RECORDING, AND INK JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
CN-116265453-A Compounds as AR inhibitors and uses thereof 南京圣和药业股份有限公司 2023-06-20 CN disclosed
US-10016981-B2 Aqueous ink set for ink jet recording, recording method, and ink jet recording apparatus SEIKO EPSON CORPORATION (JP) 2018-07-10 US disclosed
US-9944807-B2 Ink composition and ink set SEIKO EPSON CORPORATION (JP) 2018-04-17 US disclosed
US-20180001643-A1 AQUEOUS INK SET FOR INK JET RECORDING, RECORDING METHOD, AND INK JET RECORDING APPARATUS SEIKO EPSON CORPORATION (JP) 2018-01-04 US disclosed
US-9822268-B2 Ink composition SEIKO EPSON CORPORATION (JP) 2017-11-21 US disclosed
US-20170247557-A1 COMPOUND, INK, INK CARTRIDGE AND INK JET RECORDING METHOD CANON KABUSHIKI KAISHA (JP) 2017-08-31 US disclosed
US-7241332-B2 Ink jet yellow ink, ink set, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-10 US disclosed
US-7226728-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2007-06-05 US disclosed
US-20070120920-A1 Ink for inkjet, ink set for inkjet, and inkjet recording method FUJIFILM CORPORATION (JP) 2007-05-31 US disclosed
US-7223453-B2 Ink jet recording medium and ink jet recording method FUJIFILM CORPORATION (JP) 2007-05-29 US disclosed
US-7219988-B2 Water-soluble phthalocyanine compound-containing ink for ink jetting, ink jet recording method and method for improving ozone gas discoloration of colored image material FUJI PHOTO FILM CO., LTD. (JP) 2007-05-22 US disclosed
US-20070109376-A1 Ink composition, ink set and recording method FUJIFILM CORPORATION 2007-05-17 US disclosed
US-20070072136-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070015095-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. 2007-01-18 US disclosed
US-7157220-B2 Silver halide photosensitive material and photothermographic material FUJIFILM CORPORATION (JP) 2007-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170247557-A1 COMPOUND, INK, INK CARTRIDGE AND INK JET RECORDING METHOD JAK1, JAK2, ETV6 APP 4357/4885LMNA 4849/4885PTGS1 2720/4885
US-20130217670-A1 QUINOXALINE DERIVATIVES PIK3R5, NQO2, PIK3R1 APP 1739/4885LMNA 2968/4885PTGS1 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.