SCHEMBL21981982

SCHEMBL21981982

Clc1ccc(-c2cccc3ccccc23)nc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 4/20 0.48
CYP11B1 P15538 3/20 0.48
TGFBR1 P36897 2/20 0.43
MAPK14 Q16539 1/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
KMT2A Q03164 3/20 0.40
DHODH Q02127 1/20 0.40
NOS1 P29475 1/20 0.40
MEN1 O00255 2/20 0.40
BMX P51813 1/20 0.39
MAPT P10636 2/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26551585 0.81 BMX (0.43) CYP11B2CYP11B1KDM4EALDH1A1CYP1A2
SCHEMBL13979742 0.80 CYP11B1 (0.49) CYP11B2CYP11B1KDM4EALDH1A1HPGD
SCHEMBL19933734 0.80 CYP11B1 (0.41) CYP11B2CYP11B1KDM4EALDH1A1HPGD
SCHEMBL26554492 0.80 BMX (0.42) CYP11B2CYP11B1KDM4EALDH1A1CYP1A2
SCHEMBL1534980 0.79 CYP11B2 (0.48) CYP11B2CYP11B1KDM4EALDH1A1HPGD
SCHEMBL13134510 0.79 CYP11B1 (0.52) CYP11B2CYP11B1KDM4EALDH1A1HPGD
SCHEMBL25768309 0.79 NOS1 (0.43) CYP11B2CYP11B1KDM4EALDH1A1HPGD
SCHEMBL14988289 0.79 CYP11B1 (0.48) CYP11B2CYP11B1TGFBR1KDM4EALDH1A1
SCHEMBL16502663 0.77 DHODH (0.46) KDM4EALDH1A1HPGDKMT2ADHODH
SCHEMBL19794377 0.76 CYP11B1 (0.46) CYP11B2CYP11B1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed