SCHEMBL21981990

SCHEMBL21981990

Cc1cc(-c2cccc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)c2)ccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.51
WNT3A P56704 7/20 0.50
PSEN1 P49768 2/20 0.49
PSEN2 P49810 2/20 0.49
APH1B Q8WW43 2/20 0.49
NCSTN Q92542 2/20 0.49
APH1A Q96BI3 2/20 0.49
PSENEN Q9NZ42 2/20 0.49
PORCN Q9H237 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
LMNA P02545 1/20 0.45
MAP4K4 O95819 2/20 0.44
GSK3B P49841 2/20 0.44
CLK4 Q9HAZ1 2/20 0.44
ABL1 P00519 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
IGF1R P08069 1/20 0.44
LTK P29376 1/20 0.44
KDR P35968 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21982127 0.98 DYRK1A (0.50) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL17932780 0.95 L3MBTL1 (0.50) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL24403762 0.94 DYRK1A (0.49) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL16189067 0.91 WNT3A (0.49) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL8383748 0.89 DYRK1A (0.56) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL16189565 0.88 DYRK1A (0.48) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL16189237 0.88 DYRK1A (0.44) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL19543720 0.88 DYRK1A (0.46) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL17532824 0.87 WNT3A (0.41) DYRK1AWNT3APSEN1PSEN2APH1B
SCHEMBL17532827 0.87 WNT3A (0.44) DYRK1AWNT3APSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed