SCHEMBL21983438

SCHEMBL21983438

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccc2c(c1)c1cc(-n3c4ccccc4c4ccccc43)ccc1n2-c1ccc(-c2ccc(-c3cc(-c4ccccc4C)nc(-c4ccccc4C)n3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FLT3 P36888 1/20 0.36
▸ AKR1C4 P17516 1/20 0.36
▸ AKR1C3 P42330 1/20 0.36
▸ AKR1C2 P52895 1/20 0.36
▸ AKR1C1 Q04828 1/20 0.36
▸ NR3C1 P04150 1/20 0.34
▸ PGR P06401 1/20 0.34
▸ ALDH1A1 P00352 8/20 0.33
▸ KDM4E B2RXH2 7/20 0.33
▸ MAPT P10636 5/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ LMNA P02545 3/20 0.33
▸ GAA P10253 2/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ PTGER4 P35408 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ AHR P35869 1/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18679554 1.00 FLT3 (0.36) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL21983440 1.00 FLT3 (0.36) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL18679088 1.00 FLT3 (0.36) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL18679485 1.00 FLT3 (0.36) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL18679128 1.00 FLT3 (0.36) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL18679150 0.99 FLT3 (0.37) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL18679569 0.99 FLT3 (0.37) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL18679170 0.99 FLT3 (0.37) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL18679537 0.96 NR3C1 (0.37) FLT3AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL18679015 0.96 NR3C1 (0.37) FLT3AKR1C4AKR1C3AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200243773-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-07-30 — — US disclosed
US-10651392-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-05-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10651392-B2 Organic light-emitting device OR10J3, L1CAM, EML4 FLT3 3774/4885AKR1C4 3359/4885AKR1C3 3039/4885
US-20200243773-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, L1CAM, EML4 FLT3 3774/4885AKR1C4 3359/4885AKR1C3 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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