SCHEMBL2198476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12509731	0.87	PARP1 (0.40)	GAATSHRMEN1KMT2AJAK2
	SCHEMBL13446749	0.87	JAK2 (0.41)	GAAMEN1KMT2AJAK2NPC1
	SCHEMBL2202819	0.86	MEN1 (0.46)	GAATSHRMEN1KMT2AJAK2
	SCHEMBL2201731	0.85	JAK2 (0.40)	GAAMEN1KMT2AJAK2NPC1
	SCHEMBL2200789	0.84	MAPT (0.50)	GAAMEN1KMT2AJAK2NPC1
	SCHEMBL2198505	0.84	TP53 (0.40)	GAAJAK2NPC1RAB9ABRD4
	SCHEMBL2201027	0.83	HTR2C (0.39)	GAAMEN1KMT2AJAK2NPC1
	SCHEMBL2196917	0.83	JAK2 (0.41)	GAATSHRMEN1KMT2AJAK2
	SCHEMBL2198287	0.83	JAK2 (0.39)	GAAMEN1KMT2AJAK2NPC1
	SCHEMBL2200930	0.82	JAK2 (0.52)	GAAMEN1KMT2AJAK2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.