Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081419 | 0.82 | CASP3 (0.39) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL9388063 | 0.80 | KDM4E (0.43) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19960783 | 0.80 | LRRK2 (0.37) | MEN1KMT2ALMNAMAPTHSD17B10 | |
| SCHEMBL28192440 | 0.77 | ATM (0.37) | KDM4EALDH1A1 | |
| SCHEMBL15345099 | 0.74 | LMNA (0.40) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL18081377 | 0.73 | IDO1 (0.38) | — | |
| SCHEMBL23028448 | 0.72 | LMNA (0.46) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL27925795 | 0.72 | LMNA (0.38) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL15791953 | 0.72 | LMNA (0.38) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL27004836 | 0.72 | POLB (0.39) | MEN1KMT2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3269715-B1 | SUBSTITUTED 2-HYDROGEN-PYRAZOLE DERIVATIVE SERVING AS ANTICANCER DRUG | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2020-05-13 | — | — | EP | disclosed |