SCHEMBL2198518

SCHEMBL2198518

OOc1ccc(O)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.44
TYR P14679 2/20 0.42
CES2 O00748 1/20 0.41
ALOX5 P09917 2/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
SYNJ2 O15056 1/20 0.39
TTR P02766 1/20 0.39
CYP1A1 P04798 1/20 0.39
BCHE P06276 1/20 0.39
MMP2 P08253 1/20 0.39
PTPN1 P18031 1/20 0.39
PTGS1 P23219 1/20 0.39
CYP1B1 Q16678 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278391 0.81 TTR (0.50) MAOBTYRCES2ALOX5CA12
SCHEMBL13914988 0.78 MAOB (0.50) MAOBTYRCA12CA1CA2
SCHEMBL676467 0.78 MEN1 (0.56) TTRESR1MEN1KMT2AESR2
SCHEMBL68212 0.77 MAOB (0.67) MAOBCA1CA2ALDH1A1TSHR
SCHEMBL29692356 0.77 MAOB (0.67) MAOBCA1CA2ALDH1A1TSHR
SCHEMBL6954009 0.77 MAOB (0.43) MAOBTYRCES2ALOX5CA12
SCHEMBL6913382 0.75 HSD17B10 (0.54) CA12CA1CA2CA7CA9
SCHEMBL12804866 0.75 MEN1 (0.39) MAOBALOX5ALDH1A1TSHRESR1
SCHEMBL11592414 0.75 ALOX15 (0.50) CES2ALDH1A1TSHRMEN1KMT2A
SCHEMBL9645412 0.75 TTR (0.65) ALOX5TSHRTTRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116583547-A Multifunctional hydrazide crosslinking agents PPG工业俄亥俄公司 2023-08-11 CN disclosed
WO-2023090964-A1 SILVER PLATING SOLUTION (주)피이솔브 2023-05-25 WO disclosed
CN-115702189-A Composition containing thermally conductive filler PPG工业俄亥俄公司 2023-02-14 CN disclosed
US-20200181413-A1 PARTICLES WITH VARIABLE REFRACTIVE INDEX 3M INNOVATIVE PROPERTIES COMPANY 2020-06-11 US disclosed
US-7976922-B2 Optical recording medium RICOH COMPANY, LTD. (JP) 2011-07-12 US disclosed
US-7645856-B2 Ether nitrile co-polymers containing sulfonic acid groups for PEM application NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2010-01-12 US disclosed
US-7579427-B2 Synthesis of poly(arylene)s copolymers containing pendant sulfonic acid groups bonded to naphthalene as proton exchange membrane materials NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2009-08-25 US disclosed
US-20080138563-A1 Optical recording medium RICOH COMPANY, LTD. 2008-06-12 US disclosed
US-20070292731-A1 Ether nitrile co-polymers containing sulfonic acid groups for PEM application NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2007-12-20 US disclosed
US-20060004177-A1 Synthesis of poly(arylene)s copolymers containing pendant sulfonic acid groups bonded to naphthalene as proton exchange membrane materials National Research Concil of Canada (CA) 2006-01-05 US disclosed
US-5504219-A Optically active compounds and intermediates thereof, and process for manufacturing same ASAHI DENKA KOGYO K.K. (JP) 1996-04-02 US disclosed
US-5352845-A Process for manufacture of optically active saturated compounds ASAHI DENKA KOGYO K.K. (JP) 1994-10-04 US disclosed
US-5262552-A Optically active compounds and intermediates thereof, and process for manufacturing same ASAHI DENKA KOGYO K.K. (JP) 1993-11-16 US disclosed