Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18059158 | 0.80 | CDK9 (0.38) | LMNA | |
| SCHEMBL17265835 | 0.70 | DYRK1A (0.34) | — | |
| SCHEMBL17421178 | 0.67 | HSD17B10 (0.44) | KMT2ARXFP1LMNA | |
| SCHEMBL18506073 | 0.64 | POLB (0.46) | KMT2ALMNA | |
| SCHEMBL11946715 | 0.62 | CYP1A2 (0.47) | KMT2ARXFP1LMNA | |
| SCHEMBL11946717 | 0.62 | RAB9A (0.43) | KMT2ALMNA | |
| SCHEMBL17421055 | 0.62 | AAK1 (0.37) | — | |
| SCHEMBL18506141 | 0.61 | CYP3A4 (0.34) | KMT2ARXFP1 | |
| SCHEMBL23005906 | 0.61 | — | — | |
| SCHEMBL12724791 | 0.61 | KDM4E (0.53) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016949-B1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |