Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17784852 | 0.91 | KLKB1 (0.67) | KLKB1 | |
| SCHEMBL29365582 | 0.90 | KLKB1 (0.70) | KLKB1 | |
| SCHEMBL17784845 | 0.90 | KLKB1 (0.78) | KLKB1 | |
| Bicarbonate SCHEMBL17785352 | 0.86 | KLKB1 (0.73) | KLKB1 | |
| SCHEMBL29324563 | 0.84 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL28337074 | 0.82 | KLKB1 (0.57) | KLKB1 | |
| SCHEMBL17785372 | 0.81 | KLKB1 (0.87) | KLKB1 | |
| SCHEMBL17785269 | 0.81 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17785327 | 0.81 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17785264 | 0.81 | KLKB1 (1.00) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464271-B1 | PYRAZOLE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LTD (GB) | 2020-05-13 | — | — | EP | disclosed |