Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17905120 | 0.84 | NPC1 (0.39) | LMNAHPGDNPC1RAB9AOPRM1 | |
| SCHEMBL17905574 | 0.80 | RORC (0.36) | HPGDNPC1RAB9AOPRM1OPRL1 | |
| SCHEMBL17905119 | 0.77 | AAK1 (0.39) | LMNAHPGDNPC1RAB9AMAPT | |
| SCHEMBL17905082 | 0.74 | SMN1; SMN2 (0.42) | LMNAHPGDNPC1RAB9AMAPT | |
| SCHEMBL17905505 | 0.72 | AAK1 (0.40) | HPGDMAPTKDM4EKMT2ARORC | |
| SCHEMBL25021573 | 0.72 | LMNA (0.42) | LMNAHPGDNPC1RAB9AKDM4E | |
| SCHEMBL17896165 | 0.71 | NPC1 (0.36) | LMNANPC1RAB9AMAPTKDM4E | |
| SCHEMBL17904776 | 0.71 | NPC1 (0.36) | LMNANPC1RAB9AMAPTKDM4E | |
| SCHEMBL21850472 | 0.69 | MAPT (0.50) | LMNAHPGDNPC1RAB9AMAPT | |
| SCHEMBL21976712 | 0.68 | LMNA (0.40) | LMNAHPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |