Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360428 | 0.89 | F2 (0.47) | KDM4EALDH1A1MEN1KMT2AF2 | |
| SCHEMBL20822421 | 0.87 | HRH3 (0.44) | KDM4EALDH1A1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL18440581 | 0.81 | HRH3 (0.48) | KDM4EALDH1A1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL20143867 | 0.79 | AHR (0.59) | KDM4EALDH1A1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL7474003 | 0.78 | HRH3 (0.60) | KDM4EALDH1A1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL30076020 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1F2EPHX2PPARG | |
| SCHEMBL19360302 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1F2EPHX2PPARG | |
| SCHEMBL29654185 | 0.76 | HRH3 (0.59) | KDM4EALDH1A1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL20465141 | 0.76 | ALDH1A1 (0.53) | KDM4EALDH1A1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL19360372 | 0.76 | F2 (0.49) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3650448-A1 | INDOLE-FORMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |