Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360304 | 0.88 | F2 (0.47) | F2GPR84KIF11MEN1KMT2A | |
| SCHEMBL5882117 | 0.85 | MEN1 (0.49) | KIF11MEN1KMT2AATML3MBTL1 | |
| SCHEMBL19360428 | 0.85 | F2 (0.47) | F2GPR84KIF11MEN1KMT2A | |
| SCHEMBL978722 | 0.85 | F2 (0.62) | F2GPR84KIF11MEN1KMT2A | |
| SCHEMBL19360362 | 0.83 | IDH1 (0.46) | F2GPR84KIF11MEN1KMT2A | |
| SCHEMBL5882041 | 0.80 | MEN1 (0.56) | KIF11MEN1KMT2AKDRATM | |
| SCHEMBL5794918 | 0.80 | MEN1 (0.49) | KIF11MEN1KMT2AKDRATM | |
| SCHEMBL5881784 | 0.79 | NPC1 (0.47) | KIF11MEN1KMT2AKDRATM | |
| SCHEMBL19360455 | 0.79 | MET (0.48) | F2MEN1KMT2AKDRATM | |
| SCHEMBL7411185 | 0.78 | L3MBTL1 (0.51) | KIF11MEN1KMT2AKDRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |