Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.35 |
| ▸ | VEGFA | P15692 | 3/20 | 0.34 |
| ▸ | FLT1 | P17948 | 3/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21850395 | 0.91 | P2RX7 (0.33) | EGLN1CYP19A1 | |
| SCHEMBL25022213 | 0.91 | CYP19A1 (0.40) | EGLN1VEGFAFLT1EGLN3CYP19A1 | |
| SCHEMBL21986097 | 0.91 | PPARA (0.36) | EGLN1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21850463 | 0.91 | PPARA (0.36) | EGLN1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21850457 | 0.87 | PPARA (0.40) | EGLN1 | |
| SCHEMBL21850476 | 0.86 | PPARA (0.34) | EGLN1 | |
| SCHEMBL21850397 | 0.85 | EGLN1 (0.40) | EGLN1VEGFAFLT1EGLN3TAS1R3 | |
| SCHEMBL21850414 | 0.85 | EGLN1 (0.36) | EGLN1EGLN2FTO | |
| SCHEMBL25021326 | 0.83 | RAB9A (0.35) | ALDH1A1HTTTAS1R3TAS1R1MEN1 | |
| SCHEMBL21985613 | 0.83 | RAB9A (0.35) | ALDH1A1HTTTAS1R3TAS1R1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |