Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819884 | 0.81 | CCR1 (0.33) | — | |
| SCHEMBL26536287 | 0.78 | F2RL1 (0.37) | — | |
| SCHEMBL23937726 | 0.70 | COMT (0.33) | — | |
| SCHEMBL26536818 | 0.70 | — | — | |
| SCHEMBL27285038 | 0.70 | HSD11B1 (0.33) | — | |
| SCHEMBL18736629 | 0.67 | KDM4E (0.33) | — | |
| SCHEMBL18544894 | 0.66 | CYP2A6 (0.43) | CDK5CDK5R1 | |
| SCHEMBL16977989 | 0.66 | MGLL (0.35) | BRD4CDK5CDK5R1 | |
| SCHEMBL20987527 | 0.65 | HASPIN (0.36) | — | |
| SCHEMBL27404279 | 0.65 | PIK3CB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172214-B1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-05-13 | — | — | EP | disclosed |