Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19963222 | 0.92 | CYP1A2 (0.46) | MMECYP1A2ACETRPV1FNTA | |
| SCHEMBL19963171 | 0.88 | NPC1 (0.38) | MMECYP1A2SLC7A5ACETRPV1 | |
| SCHEMBL19963024 | 0.88 | ESR1 (0.42) | MMECYP1A2SLC7A5ACEESR1 | |
| SCHEMBL19963028 | 0.88 | MME (0.42) | MMECYP1A2SLC7A5ACETRPV1 | |
| SCHEMBL21985995 | 0.88 | POLB (0.39) | MMECYP1A2SLC7A5ACETRPV1 | |
| SCHEMBL19963029 | 0.85 | PPARG (0.41) | MMEPOLBESR1ESR2OPRD1 | |
| SCHEMBL20544661 | 0.84 | CRHBP (0.43) | ANPEPERAP2ERAP1CPA1 | |
| SCHEMBL19963038 | 0.82 | ANPEP (0.38) | CYP1A2ANPEPERAP2ERAP1ESR1 | |
| SCHEMBL19963100 | 0.82 | LMNA (0.43) | CYP1A2TRPV1ANPEPERAP2ERAP1 | |
| SCHEMBL29594467 | 0.82 | LMNA (0.43) | CYP1A2TRPV1ANPEPERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395804-B1 | NOVEL SPIROQUINONE DERIVATIVE COMPOUND, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS WHICH CONTAINS SAME AS ACTIVE INGREDIENT | UNIV GACHON IND ACAD COOP FOUND (KR) | 2020-05-13 | — | — | EP | disclosed |