Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13417649 | 0.87 | ATM (0.57) | POLBUSP2L3MBTL1MEN1KMT2A | |
| SCHEMBL10080556 | 0.85 | ALDH1A1 (0.67) | POLBKDM4EGAAMEN1KMT2A | |
| SCHEMBL24899730 | 0.79 | POLB (0.64) | POLBKDM4EGAAUSP2L3MBTL1 | |
| SCHEMBL2977562 | 0.79 | POLB (0.97) | POLBKDM4EGAAUSP2L3MBTL1 | |
| SCHEMBL21925711 | 0.79 | POLB (0.59) | POLBKDM4EGAAUSP2L3MBTL1 | |
| SCHEMBL30586418 | 0.78 | KMT2A (0.67) | POLBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17646020 | 0.78 | POLB (0.67) | POLBKDM4EGAAUSP2L3MBTL1 | |
| SCHEMBL14134639 | 0.78 | POLB (1.00) | POLBKDM4EGAAUSP2L3MBTL1 | |
| SCHEMBL15274602 | 0.78 | POLB (0.61) | POLBKDM4EGAAUSP2L3MBTL1 | |
| SCHEMBL29944146 | 0.77 | POLB (0.65) | POLBKDM4EGAAUSP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387949-A1 | NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS | UNIV NANTES (FR) | 2021-12-16 | — | — | US | disclosed |
| EP-3650447-A1 | NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS | Universite de Nantes (FR) | 2020-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387949-A1 | NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS | CHRM3, CHRNA3, CHRNB3 | POLB 4794/4885KDM4E 2823/4885GAA 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.