SCHEMBL21986454

SCHEMBL21986454

CC1=CCC(C)(Nc2ccc(N)cc2)C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6282920 0.92
SCHEMBL24591447 0.73 NR4A1 (0.31)
SCHEMBL5835182 0.73 HSD11B1 (0.33)
SCHEMBL31453495 0.73 TP53 (0.30)
SCHEMBL18469061 0.67
SCHEMBL4779737 0.66 HSD11B1 (0.31)
SCHEMBL23179690 0.66 MEN1 (0.31)
SCHEMBL15912431 0.65 MAPT (0.38)
SCHEMBL21524288 0.65
SCHEMBL31219260 0.65 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113348205-B Method for stabilizing halogen-free thermoplastic recyclates, plastic compositions, stabilizer compositions and use of stabilizer compositions 弗劳恩霍夫应用研究促进协会 2024-02-27 CN disclosed
CN-117355567-A Use of at least one sulfur-containing amino acid for stabilizing thermoplastic recycling material, stabilized thermoplastic recycling material, stabilizer composition, masterbatch and molding compound or molded part 弗劳恩霍夫应用研究促进协会 2024-01-05 CN disclosed
CN-117120561-A Low dielectric resin composition and articles made therefrom 亨斯迈先进材料许可(瑞士)有限公司 2023-11-24 CN disclosed
CN-113348205-A Method for stabilizing halogen-free thermoplastic recyclates, plastic composition, stabilizer composition and use of stabilizer composition 弗劳恩霍夫应用研究促进协会 2021-09-03 CN disclosed
CN-113166470-A Method for stabilizing virgin thermoplastic materials and stabilized plastic compositions, molding compounds and moldings produced therefrom, stabilizer composition and use thereof 弗劳恩霍夫应用研究促进协会 2021-07-23 CN disclosed
CN-107835841-B Crystallization-retarded polymer composition, additive composition influencing crystallization behavior and use, method for reducing crystallization point 弗劳恩霍弗应用研究促进协会 2021-01-05 CN disclosed
EP-3658616-A1 HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2020-06-03 EP disclosed
CN-1437630-A Stabilizer mixture CIBA SC HOLDING AG (CH) 2003-08-20 CN disclosed