SCHEMBL21986552

SCHEMBL21986552

BC(C)(CCC(=O)O)OCCC(C)(C)N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
THRB P10828 1/20 0.39
KMT2A Q03164 1/20 0.39
NAALAD2 Q9Y3Q0 1/20 0.34
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 2/20 0.33
S1PR4 O95977 1/20 0.33
ACE P12821 1/20 0.32
ESR1 P03372 1/20 0.32
CYP3A4 P08684 1/20 0.32
ESR2 Q92731 1/20 0.32
GRM4 Q14833 1/20 0.31
CHEK1 O14757 1/20 0.30
FYN P06241 1/20 0.30
PDGFRB P09619 1/20 0.30
PIM1 P11309 1/20 0.30
FGFR1 P11362 1/20 0.30
FLT1 P17948 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4967281 0.81 ALDH1A1 (0.41) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL25498801 0.80 CYP1A2 (0.32) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL22768991 0.77 ALDH1A1 (0.46) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL20033557 0.77 GRM4 (0.30) GRM4
SCHEMBL1933286 0.76
SCHEMBL20033563 0.75
Hydrochloric Acid SCHEMBL10901865 0.74 ALDH1A1 (0.52) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL26438963 0.73 S1PR1 (0.34) ALDH1A1MEN1KMT2ANAALAD2S1PR1
SCHEMBL14279904 0.72 HMGCR (0.38) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL20629972 0.68 TSHR (0.35) ALDH1A1MEN1CYP1A2THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3650464-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND XDCExplorer (Shanghai) Co., Ltd. (CN) 2020-05-13 EP disclosed