Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22059589 | 0.87 | TSHR (0.36) | TSHRFOLH1ALDH1A1MEN1CYP1A2 | |
| SCHEMBL22060197 | 0.81 | TSHR (0.43) | TSHRFOLH1ALDH1A1MEN1KMT2A | |
| SCHEMBL4967281 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1S1PR1S1PR3MEN1 | |
| SCHEMBL22060217 | 0.78 | FOLH1 (0.41) | TSHRFOLH1ALDH1A1 | |
| SCHEMBL20630604 | 0.76 | FOLH1 (0.39) | TSHRFOLH1 | |
| SCHEMBL20630504 | 0.74 | FOLH1 (0.37) | TSHRFOLH1 | |
| SCHEMBL14279904 | 0.72 | HMGCR (0.38) | TSHRALDH1A1S1PR1S1PR3MEN1 | |
| SCHEMBL2227903 | 0.69 | LMNA (0.48) | TSHRALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL225702 | 0.69 | TSHR (0.71) | TSHRFOLH1ALDH1A1CYP1A2THRB | |
| SCHEMBL94565 | 0.69 | TSHR (0.71) | TSHRFOLH1ALDH1A1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3650464-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | XDCExplorer (Shanghai) Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019007383-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | 凯惠科技发展(上海)有限公司 | 2019-01-10 | — | — | WO | disclosed |