⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504245 | 0.73 | MAPT (0.32) | — | |
| SCHEMBL7857536 | 0.68 | LMNA (0.38) | — | |
| SCHEMBL10493356 | 0.66 | LMNA (0.60) | — | |
| SCHEMBL9502375 | 0.66 | MEN1 (0.36) | — | |
| SCHEMBL8772116 | 0.66 | — | — | |
| SCHEMBL18944170 | 0.65 | PDE4A (0.52) | — | |
| SCHEMBL4219581 | 0.65 | LMNA (0.35) | — | |
| SCHEMBL19614818 | 0.65 | MAPT (0.39) | — | |
| SCHEMBL9810926 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL1088645 | 0.64 | HSD17B10 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768438-A1 | IN-SITU THIN COATING OF OXIDE PARTICLES ONTO SURFACES AND THEIR APPLICATIONS | Bar Ilan University (IL) | 2021-01-27 | — | — | EP | disclosed |
| US-20200171534-A1 | IN-SITE THIN COATING OF SILICA PARTICLES ONTO PLASTIC FILMS AND THEIR APPLICATIONS | BAR-ILAN UNIVERSITY (IL) | 2020-06-04 | — | — | US | disclosed |