Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988644 | 0.87 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL21989035 | 0.87 | KCNH2 (0.48) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL30046304 | 0.87 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL21988643 | 0.87 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL21989072 | 0.87 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL16869457 | 0.78 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL16869458 | 0.78 | KDM4E (0.54) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL21988886 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL24554592 | 0.76 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL25046978 | 0.76 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12103921-B2 | Chemical compounds | PFIZER INC. (US) | 2024-10-01 | — | — | US | disclosed |
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20220348555-A1 | Chemical Compounds | PFIZER INC. (US) | 2022-11-03 | — | — | US | disclosed |
| EP-3886984-A1 | PYRAZOLES AS MODULATORS OF HEMOGLOBIN | Pfizer Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| US-11014908-B2 | Chemical compounds | PFIZER INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200172512-A1 | Chemical Compounds | PFIZER INC. (US) | 2020-06-04 | — | — | US | disclosed |
| WO-2020109994-A1 | PYRAZOLES AS MODULATORS OF HEMOGLOBIN | PFIZER INC. (US) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172512-A1 | Chemical Compounds | HBZ, HBB, HBS1L | MAPT 305/4885MEN1 3178/4885KMT2A 3842/4885 |
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | MAPT 305/4885MEN1 3178/4885KMT2A 3842/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | MAPT 305/4885MEN1 3178/4885KMT2A 3842/4885 |
| US-12103921-B2 | Chemical compounds | HBZ, HBB, HBS1L | MAPT 305/4885MEN1 3178/4885KMT2A 3842/4885 |
| US-11014908-B2 | Chemical compounds | HBZ, HBB, HBS1L | MAPT 305/4885MEN1 3178/4885KMT2A 3842/4885 |
| US-20220348555-A1 | Chemical Compounds | HBZ, HBB, HBS1L | MAPT 305/4885MEN1 3178/4885KMT2A 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.