Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | PPARD | Q03181 | 8/20 | 0.49 |
| ▸ | PPARA | Q07869 | 8/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.49 |
| ▸ | FABP4 | P15090 | 4/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isometheptene SCHEMBL17316005 | 0.88 | ALDH1A1 (0.71) | ALDH1A1ALOX15ATMTSHR | |
| Isometheptene SCHEMBL3927395 | 0.80 | ALDH1A1 (0.73) | ALDH1A1ALOX15USP2ATMTSHR | |
| Stearic Acid SCHEMBL27481061 | 0.78 | GPR84 (0.63) | ALDH1A1PPARGPPARDPPARAPTPN1 | |
| Dexisometheptene SCHEMBL15894912 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TDP1ALOX15KMT2AUSP2 | |
| Isometheptene SCHEMBL148619 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TDP1ALOX15KMT2AUSP2 | |
| SCHEMBL11543742 | 0.76 | TSHR (0.50) | ALDH1A1PPARGPPARDPPARAPTPN1 | |
| Isometheptene SCHEMBL2820117 | 0.76 | ALDH1A1 (0.66) | ALDH1A1TDP1ALOX15KMT2AUSP2 | |
| Decanoic Acid SCHEMBL1833740 | 0.74 | GPR84 (0.68) | ALDH1A1PPARGPPARDPPARAPTPN1 | |
| Nonanoate SCHEMBL1830989 | 0.74 | GPR84 (0.68) | ALDH1A1PPARGPPARDPPARAPTPN1 | |
| Heptanoate SCHEMBL1839048 | 0.74 | GPR84 (0.68) | ALDH1A1PPARGPPARDPPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11090237-B2 | Deodorant cosmetic compositions comprising calcium silicate and sodium bicarbonate | HENKEL AG & CO. KGAA (DE) | 2021-08-17 | — | — | US | disclosed |
| US-20200170901-A1 | DEODORANT COSMETIC COMPOSITIONS COMPRISING CALCIUM SILICATE AND SODIUM BICARBONATE | HENKEL AG & CO. KGAA (DE) | 2020-06-04 | — | — | US | disclosed |
| US-20200170896-A1 | ANHYDROUS DEODORANT COSMETIC COMPOSITIONS COMPRISING CALCIUM CARBONATE | HENKEL AG & CO. KGAA (DE) | 2020-06-04 | — | — | US | disclosed |