Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.51 |
| ▸ | CPT1A | P50416 | 2/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.47 |
| ▸ | CPT2 | P23786 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21990074 | 0.88 | STING1 (0.51) | LMNAL3MBTL1TSHRSTING1CPT1A | |
| SCHEMBL31411676 | 0.85 | CPT1A (0.48) | LMNAL3MBTL1TSHRSTING1CPT1A | |
| SCHEMBL25943090 | 0.83 | STING1 (0.61) | LMNAL3MBTL1TSHRSTING1CPT1A | |
| SCHEMBL25809782 | 0.83 | STING1 (0.72) | TSHRSTING1CPT1ACPT1BCPT2 | |
| SCHEMBL20594649 | 0.82 | LMNA (0.51) | LMNAL3MBTL1TSHRSTING1MAPT | |
| SCHEMBL25942338 | 0.82 | STING1 (0.55) | LMNAL3MBTL1TSHRSTING1CPT1A | |
| SCHEMBL21989994 | 0.82 | STING1 (0.75) | STING1CPT1ACPT1BCPT2MAPT | |
| SCHEMBL29825029 | 0.82 | STING1 (0.50) | LMNAL3MBTL1STING1CPT1ACPT1B | |
| SCHEMBL31411646 | 0.80 | CPT1A (0.43) | LMNAL3MBTL1TSHRSTING1CPT1A | |
| SCHEMBL21990107 | 0.80 | POLB (0.64) | LMNAL3MBTL1TSHRSTING1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172483-A1 | HETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2020-06-04 | — | — | US | disclosed |
| US-20200172483-A1 | HETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172483-A1 | HETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING | STING1, IRF3, CGAS | LMNA 4251/4885L3MBTL1 2965/4885TSHR 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.