Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381676 | 0.81 | TAAR1 (0.56) | TAAR1EPHX2EPHX1ALDH1A1CYP2C19 | |
| SCHEMBL6386709 | 0.81 | TAAR1 (0.56) | TAAR1EPHX2EPHX1ALDH1A1CYP2C19 | |
| SCHEMBL6386712 | 0.81 | TAAR1 (0.56) | TAAR1EPHX2EPHX1ALDH1A1CYP2C19 | |
| SCHEMBL9177083 | 0.75 | DPP4 (0.51) | TAAR1EPHX2EPHX1ALDH1A1CYP2C19 | |
| SCHEMBL7876555 | 0.75 | DPP4 (0.51) | TAAR1EPHX2EPHX1ALDH1A1CYP2C19 | |
| SCHEMBL7876558 | 0.75 | TAAR1 (0.46) | TAAR1EPHX2EPHX1ALDH1A1CYP2C19 | |
| SCHEMBL5880795 | 0.75 | ALDH1A1 (0.60) | TAAR1EPHX2EPHX1ALDH1A1CYP2C19 | |
| SCHEMBL991353 | 0.74 | TAAR1 (0.65) | TAAR1EPHX2EPHX1ALDH1A1NPC1 | |
| SCHEMBL3641064 | 0.74 | TAAR1 (0.65) | TAAR1EPHX2EPHX1ALDH1A1NPC1 | |
| SCHEMBL991352 | 0.74 | TAAR1 (0.65) | TAAR1EPHX2EPHX1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977362-B2 | Alpha-(N-benzenesulfonamido)cycloalkyl derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-07-12 | — | — | US | disclosed |