Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876555 | 1.00 | DPP4 (0.51) | DPP4DPP7TAAR1ALDH1A1L3MBTL1 | |
| SCHEMBL7876558 | 0.77 | TAAR1 (0.46) | DPP4DPP7TAAR1ALDH1A1L3MBTL1 | |
| SCHEMBL5880795 | 0.76 | ALDH1A1 (0.60) | TAAR1ALDH1A1L3MBTL1CYP2C19KEAP1 | |
| SCHEMBL2199017 | 0.75 | TAAR1 (0.48) | TAAR1ALDH1A1L3MBTL1CYP2C19KEAP1 | |
| SCHEMBL11880887 | 0.74 | ALDH1A1 (0.63) | TAAR1ALDH1A1L3MBTL1CYP2C19KEAP1 | |
| SCHEMBL1026541 | 0.73 | NPC1 (0.42) | DPP4DPP7TAAR1ALDH1A1L3MBTL1 | |
| SCHEMBL14036245 | 0.73 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1CYP2C19KEAP1FFAR1 | |
| SCHEMBL27109144 | 0.72 | KEAP1 (0.57) | ALDH1A1L3MBTL1CYP2C19KEAP1FFAR1 | |
| SCHEMBL9175723 | 0.69 | POLB (0.61) | TAAR1ALDH1A1KEAP1FFAR1TDP1 | |
| SCHEMBL9175728 | 0.69 | POLB (0.61) | TAAR1ALDH1A1KEAP1FFAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411333-B1 | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-05-31 | — | — | EP | disclosed |