SCHEMBL21990563

SCHEMBL21990563

C=C(C)C(N)=O.O=S(=O)(O)C=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
GLA P06280 1/20 0.44
HTT P42858 1/20 0.44
PPARG P37231 4/20 0.42
PTGS2 P35354 3/20 0.40
PTGS1 P23219 2/20 0.40
LMNA P02545 2/20 0.40
NFE2L2 Q16236 2/20 0.40
KMT2A Q03164 1/20 0.40
GAA P10253 1/20 0.39
CYP2C19 P33261 1/20 0.39
HDAC3 O15379 1/20 0.39
TNKS O95271 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL19856372 0.90 TDP1 (0.47) TDP1GLAHTTPPARGLMNA
Methacrylic Acid SCHEMBL8916077 0.90 TDP1 (0.47) TDP1GLAHTTPPARGLMNA
SCHEMBL19205765 0.88 GLA (0.47) TDP1GLAHTTPPARGLMNA
Methacrylic Acid SCHEMBL27797874 0.86 GLA (0.43) TDP1GLAHTTPPARGPTGS2
Styrene SCHEMBL7711611 0.84 ALDH1A1 (0.42) TDP1GLAHTTPPARGLMNA
Acrylamide SCHEMBL8742738 0.83 HTT (0.43) TDP1GLAHTTPPARGLMNA
SCHEMBL20474516 0.83 HTT (0.43) TDP1GLAHTTPPARGLMNA
SCHEMBL10777428 0.83 HTT (0.43) TDP1GLAHTTPPARGLMNA
SCHEMBL28298872 0.83 PPARG (0.45) TDP1GLAHTTPPARGLMNA
Ethylene SCHEMBL131455 0.82 PPARG (0.50) HTTPPARGLMNANFE2L2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3666753-B1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF TOSOH FINECHEM CORP (JP) 2024-09-11 EP disclosed
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof TOSOH FINECHEM CORPORATION (JP) 2022-10-04 US disclosed
CN-110997631-B High purity amphiphilic arylsulfonic acid amine salt vinyl monomers and (co) polymers thereof 东曹精细化工株式会社 2022-07-15 CN disclosed
EP-3666753-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF Tosoh Finechem Corporation (JP) 2020-06-17 EP disclosed
US-20200172643-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF TOSOH FINECHEM CORPORATION (JP) 2020-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof SLC7A1, ARSA, STS TDP1 3230/4885GLA 4817/4885HTT 112/4885
US-20200172643-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF SLC7A1, ARSA, STS TDP1 3230/4885GLA 4817/4885HTT 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.