Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ramiprilat SCHEMBL4634176 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9285191 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL467411 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL5490942 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL10590419 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9438804 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL5490939 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9594279 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL4733176 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9438808 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886817-A1 | PHARMACEUTICAL COMPOSITION COMPRISING RAMIPRIL AND INDAPAMIDE | Zaklady Farmaceutyczne Polpharma S.A. (PL) | 2021-10-06 | — | — | EP | claimed |
| WO-2020109319-A1 | PHARMACEUTICAL COMPOSITION COMPRISING RAMIPRIL AND INDAPAMIDE | ZAKLADY FARMACEUTYCZNE POLPHARMA S.A (PL) | 2020-06-04 | — | — | WO | claimed |
| EP-3886817-A1 | PHARMACEUTICAL COMPOSITION COMPRISING RAMIPRIL AND INDAPAMIDE | Zaklady Farmaceutyczne Polpharma S.A. (PL) | 2021-10-06 | — | — | EP | disclosed |
| EP-3886817-A1 | PHARMACEUTICAL COMPOSITION COMPRISING RAMIPRIL AND INDAPAMIDE | Zaklady Farmaceutyczne Polpharma S.A. (PL) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109319-A1 | PHARMACEUTICAL COMPOSITION COMPRISING RAMIPRIL AND INDAPAMIDE | ZAKLADY FARMACEUTYCZNE POLPHARMA S.A (PL) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020109319-A1 | PHARMACEUTICAL COMPOSITION COMPRISING RAMIPRIL AND INDAPAMIDE | ZAKLADY FARMACEUTYCZNE POLPHARMA S.A (PL) | 2020-06-04 | — | — | WO | disclosed |