Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ramiprilat SCHEMBL4634176 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9285191 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL467411 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL10590419 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9438804 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL5490939 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9594279 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL4733176 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL21990787 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9438808 | 1.00 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232680-A1 | PREPARATION OF RAMIPRIL AND STABLE PHARMACEUTICAL COMPOSITIONS | DR. REDDY'S LABORATORIES, INC. | 2007-10-04 | — | — | US | disclosed |
| US-20020077328-A1 | Selective cyclooxygenase-2 inhibitors and vasomodulator compounds for generalized pain and headache pain | PHARMACIA CORPORATION | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077328-A1 | Selective cyclooxygenase-2 inhibitors and vasomodulator compounds for generalized pain and headache pain | PTGIR, VASP, TRPV2 | ACE 965/4885MEN1 2664/4885KMT2A 2847/4885 |
| US-20070232680-A1 | PREPARATION OF RAMIPRIL AND STABLE PHARMACEUTICAL COMPOSITIONS | REN, ADRA2A, CYP3A5 | ACE 19/4885MEN1 3179/4885KMT2A 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.