Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988565 | 0.84 | LMNA (0.31) | TSHR | |
| SCHEMBL6425935 | 0.84 | AKR1B1 (0.48) | AKR1B1TSHRFFAR4FFAR1GPR84 | |
| SCHEMBL6429527 | 0.82 | FFAR4 (0.53) | AKR1B1TSHRFFAR4FFAR1GPR84 | |
| SCHEMBL6425358 | 0.82 | AKR1B1 (0.45) | AKR1B1TSHRFFAR4FFAR1GPR84 | |
| SCHEMBL20630604 | 0.80 | FOLH1 (0.39) | TSHRFOLH1 | |
| SCHEMBL9489370 | 0.78 | FFAR4 (0.56) | AKR1B1TSHRFFAR4FFAR1GPR84 | |
| SCHEMBL9487311 | 0.77 | AKR1B1 (0.48) | AKR1B1TSHRFFAR4FFAR1GPR84 | |
| SCHEMBL20630525 | 0.77 | FOLH1 (0.41) | TSHRFOLH1ALDH1A1 | |
| SCHEMBL20629973 | 0.76 | AKR1B1 (0.61) | AKR1B1TSHRFFAR4FFAR1GPR84 | |
| SCHEMBL10781727 | 0.76 | DGKA (0.50) | AKR1B1TSHRFFAR4FFAR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3650464-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | XDCExplorer (Shanghai) Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |