Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17624675 | 0.63 | — | — | |
| SCHEMBL14336833 | 0.61 | CHRM2 (0.53) | HTR3EMEN1HTR3BCYP1A2CYP2D6 | |
| SCHEMBL2009311 | 0.60 | CYP1A2 (0.62) | HTR3EMEN1HTR3BCYP1A2CYP2D6 | |
| SCHEMBL13419067 | 0.59 | CYP3A4 (0.63) | HTR3EMEN1HTR3BCYP1A2CYP2D6 | |
| SCHEMBL23323432 | 0.59 | PTPN11 (0.49) | HTR3EMEN1HTR3BCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL28561484 | 0.58 | PTPN11 (0.48) | HTR3EMEN1HTR3BCYP1A2CYP2D6 | |
| SCHEMBL5754417 | 0.58 | HTR3E (0.33) | HTR3EMEN1HTR3BCYP1A2CYP2D6 | |
| SCHEMBL3060190 | 0.58 | HTR3E (0.53) | HTR3EMEN1HTR3BCYP1A2CYP2D6 | |
| SCHEMBL20129679 | 0.57 | ALDH1A1 (0.60) | HTR3EHTR3BCYP1A2CYP2D6HTR3A | |
| SCHEMBL10055159 | 0.57 | TSHR (0.46) | HTR3EMEN1HTR3BCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3646886-A1 | TREATMENT OF PAIN WITH SEROTONIN-3 RECEPTOR AGONIST | Osaka University (JP) | 2020-05-06 | — | — | EP | disclosed |