Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTR1F | P30939 | 2/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17784096 | 0.91 | NPC1 (0.39) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL17784094 | 0.91 | NPC1 (0.39) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL17784148 | 0.91 | NPC1 (0.39) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL17792069 | 0.88 | RARA (0.38) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL17792112 | 0.88 | RARA (0.38) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL17792070 | 0.88 | RARA (0.38) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL18644420 | 0.87 | MAOB (0.38) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL17784050 | 0.87 | RARA (0.37) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL17792077 | 0.86 | LMNA (0.39) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL17784102 | 0.86 | MAPT (0.45) | RARARARBRARGNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227262-B1 | SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT | NOVIRA THERAPEUTICS INC (US) | 2020-05-13 | — | — | EP | disclosed |