SCHEMBL2199125

SCHEMBL2199125

O=C(O)CCCc1ccco1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.52
HDAC3 O15379 1/20 0.52
ADRA1A P35348 1/20 0.52
HDAC4 P56524 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HDAC1 Q13547 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC10 Q969S8 1/20 0.52
HDAC11 Q96DB2 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
HDAC9 Q9UKV0 1/20 0.52
HDAC5 Q9UQL6 1/20 0.52
ALDH1A1 P00352 11/20 0.48
MAPT P10636 8/20 0.48
KDM4E B2RXH2 8/20 0.48
HSD17B10 Q99714 7/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11635247 0.98 MAPK1 (0.50) MAPK1HDAC3ADRA1AHDAC4SLC6A3
SCHEMBL9705770 0.94 MAPT (0.52) MAPK1HDAC3ADRA1AHDAC4SLC6A3
SCHEMBL11912385 0.93 MAPT (0.55) MAPK1HDAC3ADRA1AHDAC4SLC6A3
SCHEMBL11460690 0.93 MAPT (0.55) MAPK1HDAC3ADRA1AHDAC4SLC6A3
SCHEMBL8091454 0.93 MAPT (0.55) MAPK1HDAC3ADRA1AHDAC4SLC6A3
SCHEMBL8093637 0.93 MAPT (0.55) MAPK1HDAC3ADRA1AHDAC4SLC6A3
SCHEMBL16124206 0.93 MAPT (0.55) MAPK1HDAC3ADRA1AHDAC4SLC6A3
SCHEMBL11722021 0.93 MAPT (0.55) MAPK1HDAC3ADRA1AHDAC4SLC6A3
SCHEMBL236223 0.88 ALDH1A1 (0.54) MAPK1ALDH1A1MAPTKDM4EHSD17B10
Hydrochloric Acid SCHEMBL27401794 0.86 ALDH1A1 (0.52) MAPK1ALDH1A1MAPTKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114563491-B Method for monitoring sample quality change in donkey-hide gelatin processing technology 山东师范大学 2024-08-20 CN claimed
CN-109789600-B Aerosol container made of plastic 阿尔温莱纳股份有限两合公司阿尔普拉工厂 2021-09-28 CN claimed
EP-0790974-B1 SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS BAYER AG (US) 2002-08-14 EP claimed
US-4609739-A Synthetic routes to benzofurans and benzothiophenes and intermediates therefor THE UPJOHN COMPANY (US) 1986-09-02 US claimed
EP-4593888-A1 CROSSLINKED RADIOPAQUE NETWORKS FOR MEDICAL APPLICATIONS Boston Scientific Scimed Inc. (US) 2025-08-06 EP disclosed
CN-119947762-A Crosslinked radiopaque networks for medical applications 波士顿科学医学有限公司 2025-05-06 CN disclosed
US-20240123095-A1 CROSSLINKED RADIOPAQUE NETWORKS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-04-18 US disclosed
WO-2024073271-A1 CROSSLINKED RADIOPAQUE NETWORKS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-04-04 WO disclosed
CN-117741006-A In-situ identification method for laser printing file species 山东政法学院 2024-03-22 CN disclosed
CN-109789600-B Aerosol container made of plastic 阿尔温莱纳股份有限两合公司阿尔普拉工厂 2021-09-28 CN disclosed
EP-3769776-A1 PEPTIDOMIMETIC MACROCYCLES Aileron Therapeutics, Inc. (US) 2021-01-27 EP disclosed
US-20200216836-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2020-07-09 US disclosed
US-5854277-A Thiophenebutanoic acid derivatives as matrix metalloprotease inhibitors BAYER CORPORATION (US) 1998-12-29 US disclosed
US-5789434-A ACID, ESTER OR AMIDE DERIVATIVES AS ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS AND REDUCTION OF CARTILAGE DETERIORATION BAYER CORPORATION (US) 1998-08-04 US disclosed
EP-0790974-A1 SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS Bayer Corporation (US) 1997-08-27 EP disclosed
US-4609739-A Synthetic routes to benzofurans and benzothiophenes and intermediates therefor THE UPJOHN COMPANY (US) 1986-09-02 US disclosed
US-4097485-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1978-06-27 US disclosed
US-4093622-A Pyridine esters of cyclopropane-carboxylic acid ZOECON CORPORATION (US) 1978-06-06 US disclosed
US-4086241-A Benzothiazolylimidazolidinone esters of furyl and thienyl substituted acids VELSICOL CHEMICAL CORPORATION (US) 1978-04-25 US disclosed
US-4061648-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240123095-A1 CROSSLINKED RADIOPAQUE NETWORKS FOR MEDICAL APPLICATIONS PAICS, RAD54L, RAD18 MAPK1 3336/4885HDAC3 3661/4885ADRA1A 464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.