Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124206 | 0.98 | MAPT (0.55) | MAPTRXFP1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL11722021 | 0.98 | MAPT (0.55) | MAPTRXFP1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL11460690 | 0.98 | MAPT (0.55) | MAPTRXFP1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL11912385 | 0.98 | MAPT (0.55) | MAPTRXFP1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL8093637 | 0.98 | MAPT (0.55) | MAPTRXFP1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL8091454 | 0.98 | MAPT (0.55) | MAPTRXFP1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL2199125 | 0.94 | MAPK1 (0.52) | MAPTRXFP1ALDH1A1TDP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11635247 | 0.93 | MAPK1 (0.50) | MAPTRXFP1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL30692340 | 0.87 | EPHX2 (0.58) | MAPTALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL236223 | 0.86 | ALDH1A1 (0.54) | MAPTALDH1A1TDP1ALOX15USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077411-A | Antiallergens, antiinflammatory agents; cardiovascular disorders, migraines, psoriasis | WARNER-LAMBERT CO. (US) | 1991-12-31 | — | — | US | claimed |
| EP-0094951-B1 | NEW PROSTACYCLINS AND PREPARATION METHOD THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-10-30 | — | — | EP | claimed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-105198930-B | The technetium-99 m labeled long-chain fatty acid derivative of three carbonyl of bipyridines and its application | 北京师范大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-102707570-B | Photosensitive resin composition, spacer and liquid crystal display element containing the same | CHI MEI CORP | 2014-08-06 | — | — | CN | disclosed |
| CN-102707570-A | Photosensitive resin composition, spacer and liquid crystal display element containing the same | CHI MEI CORP | 2012-10-03 | — | — | CN | disclosed |
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-4861791-A | Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents | STERLING DRUG INC. (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |