Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18181192 | 1.00 | ITGB2 (0.30) | ITGB2ICAM1ITGAL | |
| SCHEMBL19999818 | 0.89 | — | — | |
| SCHEMBL20007178 | 0.89 | — | — | |
| SCHEMBL21992081 | 0.88 | FPR1 (0.37) | — | |
| SCHEMBL18181183 | 0.88 | FPR1 (0.37) | — | |
| SCHEMBL19999822 | 0.86 | BMP1 (0.33) | ITGB2ICAM1ITGAL | |
| SCHEMBL18180974 | 0.86 | FPR1 (0.30) | — | |
| SCHEMBL18181360 | 0.85 | FPR1 (0.35) | — | |
| SCHEMBL18180973 | 0.85 | — | — | |
| SCHEMBL21992680 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286166-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2020-05-13 | — | — | EP | disclosed |