SCHEMBL2199293

SCHEMBL2199293

CCCC1COCC[N]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7510997 0.88 NOS1 (0.53)
SCHEMBL4686306 0.86 NOS1 (0.47)
SCHEMBL7028797 0.84 NOS1 (0.46)
SCHEMBL1609131 0.82
SCHEMBL1608120 0.82
SCHEMBL232762 0.82
SCHEMBL2917899 0.78
SCHEMBL2921369 0.78
SCHEMBL2918018 0.78 NOS1 (0.30)
SCHEMBL2911467 0.78 NOS1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1658263-B9 NOVEL AMINOBENZOPHENONE COMPOUNDS LEO PHARMA AS (DK) 2011-11-09 EP claimed
US-7977387-B2 Aminobenzophenone compounds LEO PHARMA A/S (DK) 2011-07-12 US claimed
EP-1658263-B1 NOVEL AMINOBENZOPHENONE COMPOUNDS LEO PHARMA AS (DK) 2010-06-02 EP claimed
US-7476672-B2 Acetylenic compounds useful in treating inflammatory disorders JANSSEN PHARMACEUTICA N.V. (BE) 2009-01-13 US claimed
JP-2006528597-A 2006-12-21 JP claimed
US-20060166990-A1 Novel aminobenzophenone compounds LEO PHARMA A/S (DK) 2006-07-27 US claimed
US-20060111352-A1 Acetylenic compounds useful in treating inflammatory disorders BEERS SCOTT 2006-05-25 US claimed
EP-1658263-A1 NOVEL AMINOBENZOPHENONE COMPOUNDS Leo Pharma A/S (DK) 2006-05-24 EP claimed
WO-2005009940-A1 NOVEL AMINOBENZOPHENONE COMPOUNDS LEO PHARMA A/S (DK) 2005-02-03 WO claimed
US-20050020838-A1 Acetylenic compound useful in treating inflammatory disorders JANSSEN PHARMACEUTICA, N.V. (BE) 2005-01-27 US claimed
WO-2004009531-A1 ACETYLENIC COMPOUNDS USEFUL IN TREATING INFLAMMATORY DISORDERS JANSSEN PHARMACEUTICA N.V. (BE) 2004-01-29 WO claimed
US-10370767-B2 Process for preparing alcohols by electrochemical reductive coupling BASF SE (DE) 2019-08-06 US disclosed
EP-3180459-B1 PROCESS FOR PREPARING ALCOHOLS BY ELECTROCHEMICAL REDUCTIVE COUPLING BASF SE (DE) 2019-01-09 EP disclosed
US-20170233874-A1 PROCESS FOR PREPARING ALCOHOLS BY ELECTROCHEMICAL REDUCTIVE COUPLING BASF SE (DE) 2017-08-17 US disclosed
EP-3180459-A1 PROCESS FOR PREPARING ALCOHOLS BY ELECTROCHEMICAL REDUCTIVE COUPLING BASF SE (DE) 2017-06-21 EP disclosed
US-4044040-A HYPERTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1977-08-23 US disclosed
US-3984419-A HYPOTENSIVES E. R. SQUIBB & SONS, INC. (US) 1976-10-05 US disclosed
US-3982021-A Compositions for the treatment of coronary diseases containing tetrahydronaphthyloxy-aminopropanols E. R. SQUIBB & SONS, INC. (US) 1976-09-21 US disclosed
US-3943149-A HYPOCHOLESTEREMIC, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-03-09 US disclosed
US-3935267-A CARDIOVASCULAR DISORDERS E. R. SQUIBB & SONS, INC. (US) 1976-01-27 US disclosed