Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | GBA1 | P04062 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686306 | 0.98 | NOS1 (0.47) | NOS1NOS2ALDH1A1EPHX1MEN1 | |
| SCHEMBL7510997 | 0.92 | NOS1 (0.53) | NOS1NOS2ALDH1A1EPHX1CYP1A2 | |
| SCHEMBL9432426 | 0.85 | NOS1 (0.41) | NOS1NOS2ALDH1A1EPHX1MEN1 | |
| SCHEMBL2199293 | 0.84 | — | — | |
| SCHEMBL7514850 | 0.81 | SIGMAR1 (0.40) | NOS1NOS2EPHX1 | |
| SCHEMBL7510051 | 0.79 | SIGMAR1 (0.37) | NOS1NOS2 | |
| SCHEMBL7505207 | 0.78 | GNAI3 (0.40) | NOS1NOS2ALDH1A1EPHX1 | |
| SCHEMBL7476348 | 0.77 | NOS1 (0.34) | NOS1NOS2 | |
| SCHEMBL7511880 | 0.76 | NOS1 (0.35) | NOS1NOS2 | |
| SCHEMBL1608120 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678569-B1 | Lubricating compositions with improved oxidation resistance containing a dispersant and an antioxidant | LUBRIZOL CORP (US) | 2003-02-26 | — | — | EP | disclosed |
| US-20010056042-A1 | Organophosphoryl borates and lubricants and aqueous fluids containing the same | SCHWIND JAMES J (US) | 2001-12-27 | — | — | US | disclosed |
| US-6228818-B1 | ANTI-WEAR, EXTREME PRESSURE AND FRICTION MODIFYING AGENTS | THE LUBRIZOL CORPORATION | 2001-05-08 | — | — | US | disclosed |
| EP-0610045-B1 | Use of moly dithiocarbamate as an antiwear additive for ceramic/metal interface | LUBRIZOL CORP (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5445749-A | Lubricating metal-ceramic interface with composition of carrier fluid and copper, cobalt, nickel, tungsten, titanium, manganese, molybdenum, iron, chromium, vanadium or rare earth thiocarbamate; improving wear performance | THE LUBRIZOL CORPORATION (US) | 1995-08-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0537338-B1 | THERMALLY STABLE COMPOSITIONS AND LUBRICANTS AND FUNCTIONAL FLUIDS CONTAINING THE SAME | LUBRIZOL CORP (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1992019703-A1 | THERMALLY STABLE COMPOSITIONS AND LUBRICANTS AND FUNCTIONAL FLUIDS CONTAINING THE SAME | THE LUBRIZOL CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5147572-A | Metal salt of phosphorus acid derivative, dithiocarbamate | THE LUBRIZOL CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| US-5094746-A | Metal salt of a phosphorus acid, a dithiocarbamate and a thionocarbamate | THE LUBRIZOL CORPORATION (US) | 1992-03-10 | — | — | US | disclosed |
| WO-1991019569-A1 | ORE FLOTATION PROCESS USING CARBAMATE COMPOUNDS | THE LUBRIZOL CORPORATION (US) | 1991-12-26 | — | — | WO | disclosed |
| WO-1991019570-A1 | A FLOTATION PROCESS USING A MIXTURE OF COLLECTORS | THE LUBRIZOL CORPORATION (US) | 1991-12-26 | — | — | WO | disclosed |
| US-5015368-A | Ore flotation process using carbamate compounds | THE LUBRIZOL CORPORATION (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| EP-0115334-B1 | BENZO-HETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-4594347-A | MICROBIOCIDES | OTSUKA PHARMACEUTICAL CO. LIMITED (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0115334-A1 | Benzo-heterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |