Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31322495 | 0.89 | EPAS1 (0.43) | ALDH1A1PTPRZ1LMNAEPAS1ESPL1 | |
| SCHEMBL1334378 | 0.82 | ALDH1A1 (0.54) | ALDH1A1PTPRZ1LMNAEPAS1HTT | |
| SCHEMBL31239593 | 0.81 | ALDH1A1 (0.44) | ALDH1A1PTPRZ1LMNAEPAS1ESPL1 | |
| SCHEMBL1604912 | 0.81 | ALDH1A1 (0.44) | ALDH1A1PTPRZ1LMNAEPAS1ESPL1 | |
| SCHEMBL1099385 | 0.79 | PTPRZ1 (0.58) | ALDH1A1PTPRZ1LMNAEPAS1HTT | |
| SCHEMBL17057451 | 0.71 | ALDH1A1 (0.45) | ALDH1A1PTPRZ1LMNAEPAS1HTT | |
| SCHEMBL2220389 | 0.71 | SMN1; SMN2 (0.35) | LMNASMN1; SMN2HTR2B | |
| SCHEMBL13807378 | 0.71 | ALDH1A1 (0.45) | ALDH1A1PTPRZ1LMNAEPAS1HTT | |
| SCHEMBL27703713 | 0.71 | ALDH1A1 (0.42) | ALDH1A1PTPRZ1LMNAEPAS1ESPL1 | |
| SCHEMBL8519013 | 0.69 | ALDH1A1 (0.57) | ALDH1A1PTPRZ1LMNAEPAS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348019-A1 | 1,2-DIAZETIDIN-3-ONE DERIVATIVE AND PHARMACEUTICAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |