Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.47 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951665 | 0.89 | CA2 (0.68) | ALDH1A1CA2CA1EPAS1 | |
| SCHEMBL12860655 | 0.89 | ALDH1A1 (0.48) | ALDH1A1CA2CA1EPAS1ESPL1 | |
| SCHEMBL1156141 | 0.89 | ALDH1A1 (0.48) | ALDH1A1CA2CA1EPAS1ESPL1 | |
| SCHEMBL17288903 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CA2CA1EPAS1ESPL1 | |
| SCHEMBL1272213 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CA2CA1EPAS1ESPL1 | |
| SCHEMBL28224684 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CA2CA1EPAS1ESPL1 | |
| SCHEMBL686828 | 0.85 | LMNA (0.61) | ALDH1A1CA2CA1EPAS1LMNA | |
| SCHEMBL7937188 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CA2CA1EPAS1ESPL1 | |
| SCHEMBL21223052 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CA2EPAS1ESPL1P2RX1 | |
| SCHEMBL21824183 | 0.85 | P2RX1 (0.52) | ALDH1A1EPAS1P2RX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965766-A | Process for synthesizing benzoic acids | ROHM AND HAAS COMPANY (US) | 1999-10-12 | — | — | US | disclosed |