Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 9/20 | 0.72 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | CDC42 | P60953 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196380 | 0.83 | RB1 (1.00) | RB1BRD3MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL4162233 | 0.82 | RB1 (1.00) | RB1BRD3MEN1MAPTKMT2A | |
| SCHEMBL5449886 | 0.81 | RB1 (0.69) | RB1BRD3MEN1MAPTKMT2A | |
| SCHEMBL4188706 | 0.78 | RB1 (0.78) | RB1BRD3MEN1MAPTKMT2A | |
| SCHEMBL15278227 | 0.77 | GAA (0.54) | RB1SIRT1CDC42CYP2D6 | |
| Hydrochloric Acid SCHEMBL4153425 | 0.77 | RB1 (0.79) | RB1BRD3MEN1MAPTKMT2A | |
| SCHEMBL2320201 | 0.76 | RB1 (0.70) | RB1BRD3MEN1MAPTKMT2A | |
| SCHEMBL15265267 | 0.76 | MAPT (0.57) | RB1MEN1MAPTKMT2ASIRT1 | |
| SCHEMBL4196304 | 0.76 | RB1 (0.62) | RB1BRD3SIRT2SIRT1CDC42 | |
| SCHEMBL15265369 | 0.75 | CYP2D6 (0.60) | RB1MEN1MAPTKMT2ACDC42 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200147069-A1 | Compounds for The Reduction of The Deleterious Activity of Extended Nucleotide Repeat Containing Genes | THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147069-A1 | Compounds for The Reduction of The Deleterious Activity of Extended Nucleotide Repeat Containing Genes | NSUN2, RNMT, RRM2B | RB1 903/4885BRD3 1160/4885MEN1 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.